Publication details

Dynamic functional connectivity in prodromal dementia with Lewy body

Authors

GAJDOŠ Martin NOVÁKOVÁ Marie LAMOŠ Martin ŘÍHA Pavel REKTOROVÁ Irena MIKL Michal

Year of publication 2022
Type Conference abstract
MU Faculty or unit

Central European Institute of Technology

Citation
Description In this work, we analyzed dynamic functional connectivity in 56 subjects (25 healthy controls and 31 MCI-LB) in order to detect changes related to early signs of neurodegeneration in the fMRI in brain states related to preparation to the action. We used method called sliding window analysis. We found significant differences in dwell time in one of 4 identified brain states. This dwell time significantly correlated with visuospatial memory in MCI-LB group whereas in HC group was no significant correlation present. Observed changes probably reflect compensatory mechanisms of MCI-LB.
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