Publication details

Long-Term Efficacy and Safety of Enzalutamide Monotherapy in Elderly Patients with Metastatic Castration-Resistant Prostate Cancer: A Case Report

Authors

POKRIVČÁK Tomáš NAVRÁTIL Jiří POPRACH Alexandr STANÍK Michal KISS Igor

Year of publication 2024
Type Article in Periodical
Magazine / Source CASE REPORTS IN ONCOLOGY
MU Faculty or unit

Faculty of Medicine

Citation
Web https://karger.com/cro/article/17/1/537/898017/Long-Term-Efficacy-and-Safety-of-Enzalutamide
Doi http://dx.doi.org/10.1159/000538124
Keywords Enzalutamide; Metastatic castration-resistant prostate cancer; Aged 75 and over; Comorbidity
Description Introduction: Prostate cancer is one of the most common cancers in men. Despite the sharp rise in incidence, mortality is decreasing. ARTA preparations are preferred options for asymptomatic or mildly symptomatic patients with mCRPC. The use of enzalutamide in elderly patients with mCRPC is risky and depends on a number of factors. An increased risk of falls and fractures has been shown. Case Presentation: We present a case report of an elderly patient with mCRPC treated with enzalutamide with very good long-term tolerance and efficacy. Conclusion: Despite the older age, no reduction of therapy was necessary in the patient due to good tolerance. Administration of enzalutamide in full doses resulted in a very good effect of therapy.

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