Publication details

Extraction of Cardiac Cell Membrane Fractional -Order Capacitance from Current Response to Voltage Step

Authors

KUBANEK David KOTON Jaroslav ŠVECOVÁ Olga

Year of publication 2022
Type Article in Periodical
Magazine / Source ELEKTRONIKA IR ELEKTROTECHNIKA
MU Faculty or unit

Faculty of Medicine

Citation
Web https://eejournal.ktu.lt/index.php/elt/article/view/31151
Doi http://dx.doi.org/10.5755/j02.eie.31151
Keywords Bioimpedance; Biological system modeling; Fractional calculus
Description The aim of the article is to examine the possibilities of modeling electrical properties of cardiac cell membrane using the Cole impedance model containing a fractional-order capacitor. A method is presented to determine the parameters of the model based on the current transient response to a voltage step applied to the membrane. The method is based on the numerical minimization of the least squares error between the recorded and calculated transient response of the model using the MATLAB function fminsearch. The use of a fractional-order capacitor in the membrane model is found to result in a reduction in the modeling error compared to that of the classic capacitor.

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