Publication details

Management embolie plodovou vodou

Title in English Management of amniotic fluid embolism
Authors

PEŠKOVÁ Klára ŠTOURAČ Petr SEIDLOVÁ Dagmar

Year of publication 2024
Type Article in Periodical
Magazine / Source Anesteziologie a intenzivní medicína
MU Faculty or unit

Faculty of Medicine

Citation
web https://aimjournal.cz/artkey/aim-202402-0003_management-of-amniotic-fluid-embolism.php
Doi http://dx.doi.org/10.36290/aim.2024.023
Keywords amniotic fluid embolism; immunomodulation; treatment strategies
Attached files
Description Amniotic fluid embolism is characterized by sudden cardiorespiratory collapse during labor or soon after delivery. We present immediate management when a rapid response is critical. The appearance of disseminated intravascular coagulation confirms high suspicion of the diagnosis plausibly. We remind administration of tranexamic acid and fibrinogen. Fibrinogen is preferred over plasma to minimize the risk of volume overload. Avoidance of fluid overload is an important management principle of pulmonary hypertension and right heart failure. Inotropes and pulmonary vasodilators are the mainstays of therapy. Although the therapeutic application of C1 esterase inhibitor concentrate is proposed in articles, the real application is reported sporadically. Extracorporeal membrane oxygenation can be considered.
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