Publication details
Sinonasal Inverted Papillomas: A Single-Center Experience St. Anne’s University Hospital, Brno 2012-2022. 22nd Czech - German ENT Days 13 - 14 September 2024; Prague
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| Year of publication | 2024 |
| Type | Appeared in Conference without Proceedings |
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| Description | Introduction Sinonasal inverted papillomas (SIPs) are uncommon benign tumours arising from the Schneiderian membrane of the nasal cavity and paranasal sinuses, typically in the maxillary and ethmoid regions. Although they are considered as benign lesions, they are locally aggressive and with potential for malignant transformation. SIPs typically present with symptoms such as nasal obstruction and epistaxis. Surgical resection is the primary treatment modality for SIPs, with approaches ranging from endoscopic techniques to open surgery, depending on the extent and location of the tumour. Methods This retrospective study was conducted at St. Anne’s University Hospital, Brno, Czech Republic, covering the period from 2012 to 2022. It analysed data from 66 patients who were diagnosed with SIPs, focusing on demographics, clinical manifestations, treatment methods, histopathological results, and postoperative outcomes. The primary objective was to evaluate recurrence rate and the incidence of malignant transformation. Results Patients included 24 males and 42 females, with an average age of 57 years. Key symptoms included unilateral nasal obstruction (54 cases) and epistaxis (24 cases). Predominant tumour sites were the maxillary sinus (34 cases) and ethmoid cells (16 cases). Histopathological examination identified predominantly benign tumours (63 cases), malignant transformation was observed in 4.55% (3 cases), all synchronous. Most tumours were classified as Krouse stage III (30 cases), recurrence rate was 28.1% (16 cases). Surgical interventions comprised endoscopic resection (55 cases), combined approaches (10 cases), 1 patient was primarily treated by radiotherapy due to inoperability after histopathological verification of malignancy in SIP environment. The average disease-free interval was 21 months, with patients without recurrence followed up for an average of 28 months. Conclusion In conclusion, our study focused on sinonasal inverted papillomas, showing that most were benign with mostly unilateral nasal obstruction. The tumours were commonly found in the maxillary sinus and were typically surgically removed at an advanced stage. Patients generally remained free of the disease for 21 months after treatment. |