Mimicking brain-tumor interactions using cerebral organoids and glioblastoma spheroids to study the migration of glioblastoma cells

• Authors: FEDOROVÁ Veronika; SLOVÁČKOVÁ Jana; AMRUZ ČERNÁ Kateřina; POSPÍŠILOVÁ Veronika; SEDMÍK Jiří; CESNÁRIKOVÁ Soňa; BARÁK Martin; HENDRYCH Michal; JANČÁLEK Radim; BOHAČIAKOVÁ Dáša
• Year of publication: 2024
• Type: Appeared in Conference without Proceedings
• MU Faculty or unit: Faculty of Medicine

Attached files

• Mimicking_brain-tumor_interactions_using_cerebral_organoids_and_glioblastoma_spheroids_to_study_the_migration_of_glioblastoma_cells.pdf

• Description: Glioblastoma IDH-wildtype is the most aggressive and lethal form of brain tumor characterized by significant heterogeneity and a poor prognosis. To advance treatment strategies, better models that replicate the in vivo behavior of glioblastoma cells are essential. Such an in vitro model can then be used to study mechanisms of therapeutic resistance and screening of new drugs against glioblastoma multiforme.

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