Publication details

Visualizing the effects of SORLA mutation in Alzheimer’s disease progression

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Authors

SATKOVÁ Miriam RAŠKA Jan PLEŠINGROVÁ Klára CESNÁRIKOVÁ Soňa SEDMÍK Jiří HŘÍBKOVÁ Hana FOJTÍK Petr BOHAČIAKOVÁ Dáša

Year of publication 2024
Type Appeared in Conference without Proceedings
MU Faculty or unit

Faculty of Medicine

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Description Aim: investigate whether pathogenic mutation Y1816C in SORL1 leads to altered APP processing and enlarged endosomes in human 2D neurons and 3D organoids in vitro.
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