Publication details

Sotyku - Mechanismus účinku a účinnost v léčbě psoriázy

Title in English Sotyktu – mechanism of action and efficacy in the treatment of psoriasis
Authors

NEČAS Miroslav

Year of publication 2024
Type Conference abstract
MU Faculty or unit

Faculty of Medicine

Citation NEČAS, Miroslav. Sotyku - Mechanismus účinku a účinnost v léčbě psoriázy (Sotyktu – mechanism of action and efficacy in the treatment of psoriasis). In Trýbův dermatologický den. 2024.
Description Deukravacitinib (SOTYKTU) is a highly selective tyrosine kinase 2 (TYK2) inhibitor indicated for the treatment of moderate to severe psoriasis in adult patients eligible for systemic therapy. TYK2 signaling plays an essential role in the pathogenesis of many inflammatory diseases, including psoriasis. Deukravacitinib represents a new oral treatment option for psoriasis that is likely to be significantly more effective than apremilast.

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