Publication details
What Orangutans Can Teach Us: Plants Used for Self-medication as a Potential Source of Bioactive Substances with Antiparasitic Effects
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| Year of publication | 2023 |
| Type | Appeared in Conference without Proceedings |
| MU Faculty or unit | |
| Citation | |
| Description | The main aim of this work is the isolation, identification and examination of bioactive plant fractions with potential antiparasitic activity. These extracts are obtained from plants that are routinely eaten by orangutans. Our previous research suggests that the purpose of this consumption is self-medication. The main criteria for the plant selection are the behavioral data of the orangutans and the parasite infections thereof. The effect of these extracts on the progression of significant waterborne protozoal diseases (WBD), namely amoebiasis and giardiasis, is tested using both in vitro and in vivo methods. Moreover, the anthelmintic properties of the selected extract are investigated in vivo in a model nematode, Caenorhabditis elegans. Subsequently, activityguided fractionation is performed and active substances from these extracts are isolated and their chemical structure and biological activities are characterized. |
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