Publication details

Positive identification of the puberty-accelerating pheromone of the house mouse: the volatile ligands associating with the major urinary protein

Authors

NOVOTNY Milos MA Weidong WIESLER Don ŽÍDEK Lukáš

Year of publication 1999
Type Article in Periodical
Magazine / Source Proceedings of the Royal Society of London, Series B - Biological Sciences
MU Faculty or unit

Faculty of Science

Citation
Keywords FEMALE MICE; MUS-MUSCULUS; SYNTHETIC ANALOGS; CONSTITUENTS; RESPONSES; FAMILY
Description Five structurally diverse small ligands, all binding to the major urinary protein (MUP) of the male house mouse, show individually puberty-accelerating pheromonal activity in the recipient females. A recombinant MUP (identical structurally to the natural protein) has shown no biological activity While four of these ligands were previously implicated in oestrus synchronization (Whitten effect), the same chemosignals now appear responsible for both sexual maturation and cycling in adult females.

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