Publication details
Vliv metamfetaminu na aktivitu CYP2D1 na modelu perfundovaných jater u samců potkana Wistar albino
| Title in English | The influence of methamphetamine on the CYP2D1 activity in the isolated perfused tiver from Wistar albino male rats |
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| Authors | |
| Year of publication | 2001 |
| Type | Article in Proceedings |
| Conference | 45. Studentská vědecká konference Lékařské fakulty MU. Sborník abstrakt. |
| MU Faculty or unit | |
| Citation | |
| Field | Pharmacology and pharmaceutical chemistry |
| Keywords | methamphetamine;cytochrome P450 2D; liver; rat; |
| Description | The influence of methamphetamine (MET)on the activity of CYP 2D1 was studied in the isolated perfused rat liver. MET significantly increased the activity of the CYP isozyme after 10 days of premedication probably by the indirect mechanism, because it did not influence its activity when administered directly into the perfusion solution. |
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