Publication details

Úloha adenosinového receptoru A2 v modulaci sociálního chování myší.

Title in English The role of adenosine A2 receptors in modulation of social behaviour in mice
Authors

ŠULCOVÁ Alexandra

Year of publication 2002
Type Article in Periodical
Magazine / Source Psychiatrie
MU Faculty or unit

Faculty of Medicine

Citation
Field Pharmacology and pharmaceutical chemistry
Keywords adenosine A2 receptors - caffeine - CGS 21680 - social behaviour - mice
Description Adenosine A2 receptor knock-out mice are more agressive. In the present study caffeine, the selective antagonist at A2A receptors increased occurence of aggressive acts in male mice, while agonist of A1/A2A receptors CGS 21680 their aggressivity inhibited. The results confirm a suggestion that A2 receptors are involved in regulation of behaviour.
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