Publication details

Relation between sexual dysfunctions and CYP 2D6 activity

Authors

ŽOURKOVÁ Alexandra HADAŠOVÁ Eva

Year of publication 2002
Type Article in Periodical
Magazine / Source European psychiatry
MU Faculty or unit

Faculty of Medicine

Citation
Field Psychiatry, sexuology
Keywords depressive disorder; paroxetine; sexual dysfunctions; CYP 2D6 genotype; CYP 2D6 phenotype
Description The frequency and severity of adverse effects related to sex-life were studied in patients with depressive disorder in relationship with their CYP2D6 genotype/phenotype. Subjects in which the CYP 2D6 capacity was decreased due to the long-term paroxetine treatment reported significantly higher occurence of sexual dysfunction as evaluated by the ASEX scale.
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