Publication details
Farmakoepidemiologie fenotypu CYP 2D6 a její význam v psychiatrii
| Title in English | Pharmacoepidemiology of CYP 2D6 phenotype and its consequences in psychiatry |
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| Authors | |
| Year of publication | 2002 |
| Type | Article in Periodical |
| Magazine / Source | Klinická farmakologie a farmacie |
| MU Faculty or unit | |
| Citation | |
| Field | Pharmacology and pharmaceutical chemistry |
| Keywords | Phenotype CYP 2D6; psychiatric patients; pharmacoepidemiological study |
| Description | Determination of metabolic phenotype of CYP2D6 within the group of 121 psychiatric patients showed 8.3 % poor (PM) metabolizers, 91.7 % extensive(EM) and 0.7 % ultrarapid metabolisers(UM). Patients treated with neuroleptics showed significantly decreased metabolic capacity of CYP2D6. |
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