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Publication details
Zhodnocení dosavadních zkušeností s dynamikou aktivity CYP2D6
Title in English | Evaluation of the current experience with the dynamics of CYP2D6 activity |
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Authors | |
Year of publication | 2002 |
Type | Article in Periodical |
Magazine / Source | Psychiatrie |
MU Faculty or unit | |
Citation | |
Field | Pharmacology and pharmaceutical chemistry |
Keywords | Genetic polymorphism; CYP2D6; psychiatry; enzyme inhibition; |
Description | The study followed the dynamics of the metabolic capacity of CYP2D6 during the 28-day treatment with various psychotropic drugs. It was confirmed that the psychopharmacotherapy may change the CYP2D6 phenotype from the extensive (EM) to the poor (PM) metabolic phenotype. |
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