Publication details

Effect of chronic fluoxetine treatment on methamphetamine i.v. self-administration in rats

Authors

NOVÁKOVÁ Jana ŠULCOVÁ Alexandra

Year of publication 2002
Type Article in Periodical
Magazine / Source Behavioural Pharmacology
MU Faculty or unit

Faculty of Medicine

Citation
Field Pharmacology and pharmaceutical chemistry
Keywords fluoxetine; methamphetamine; "i.v. self-administration"; rats
Description The present study was designed to investigate the influence of chronic treatment with fluoxetine on both the training and maintenance of i.v. methamphetamine self-administration. Our results indicate that 5-HT re-uptake inhibition by fluoxetine may suppress either reinforcing mechanisms or sensitization to methamphetamine eliciting drug-wanting behaviour.
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