Kineticky a termodynamicky kontrolovaný průběh domino reakce - Syntéza nových 1,3-oxathiolů a 1,3-thiazolů

• Title in English: Kinetically and Thermodynamically Controlled Domino-reaction - Synthesis of Novel 1,3-Oxathioles and 1,3-Thiazoles
• Authors: PAZDERA Pavel; FATHALLA Walid
• Year of publication: 2002
• Type: Article in Periodical
• Magazine / Source: Chemické Listy
• MU Faculty or unit: Faculty of Science
• Field: Organic chemistry
• Keywords: Domino-reaction; Cascade-reaction; Quinazoline; Oxathiole; Thiazole
• Description: New two-component domino reaction of 1,1-disubstituted-3-(2-phenyl-3H-quinazolin-4-yliden)thioureas with phenacylbromides giving quinazolin-4-yl-1,3-thiazoles as kinetically controlled and quinazolin-4-yl-1,3-oxathioles as thermodynamically controlled products is described.

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