Publication details

Quantitative Analysis of Chiral Compounds from Unresolved Peaks in Capillary Electrophoresis using Multivariate Calibration with Experimental Design and Artificial Neural Networks

Authors

DOHNAL Vlastimil LI Hua FARKOVÁ Marta HAVEL Josef

Year of publication 2002
Type Article in Periodical
Magazine / Source Chirality
MU Faculty or unit

Faculty of Science

Citation
Field Analytic chemistry
Description Quantitation of optical isomers can be achieved even from incompletely resolved peaks with a multivariate calibration applying a combination of experimental design and artificial neural networks (ANN). Using the proposed approach, method development can be more efficient and analysis time shortened while quantitation of optical isomers with acceptable precision (+-1-3%) can be achieved.

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