Publication details

Determination of 5-methyl-2'-deoxycytidine 5'-monophosphate and 2'-deoxycytidine 5'-monophosphate in the cell homogenate using HPLC

Authors

HAVLIŠ Jan DOHNAL Vlastimil REVILLA VÁZQUEZ Alma Luísa KOZÁK Libor HAVEL Josef

Year of publication 1999
Type R&D Presentation
MU Faculty or unit

Faculty of Science

Citation
Description MALDI-TOF MS is a suitable method for extremely fast semi-quantitative determination of purines and pyrimidines in urine. MVA (multivariate approach), represented by experimental design combined with ANN, is a more correct approach to optimization of the separation conditions than that of classical SVA (single variation method) and enables faster optimization of the method with lower number of experiments.
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