Publication details
DNA Interactions of New Antitumor Aminophosphine Platinum (II) Complexes
| Authors | |
|---|---|
| Year of publication | 1999 |
| Type | Article in Periodical |
| Magazine / Source | Molecular Pharmacology |
| MU Faculty or unit | |
| Citation | |
| web | http://molpharm.aspetjournals.org/ |
| Field | Biophysics |
| Keywords | DNA; platinum complexes; modification; biophysical analysis |
| Description | DNA binding of two novel platinum complexes was studied by biophysical methods. DNA binding manner was different from that of cisplatin. It is suggested that the activity profile of these compounds which is different from cisplatin might be associated with their specific DNA binding properties. |