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Publication details
A comparison of DNA binding profiles of dinuclear platinum compounds with polyamine linkers and the trinuclear platinum phase II clinical agent BBR3464
Authors | |
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Year of publication | 2002 |
Type | Article in Periodical |
Magazine / Source | Journal of Biological Inorganic Chemistry |
MU Faculty or unit | |
Citation | |
web | http://link.springer.de/link/service/journals/00775/tocs/t2007004.htm |
Field | Biophysics |
Keywords | unwinding; dinuclear platinum; hydrogen bonding; cross-links |
Description | The dNA binding profiles of three bisplatinum polyamine-linked compounds were compared with that of antitumor efficient trisplatinum compound BBR3464. It was found that their binding manner is similar. |