Unusual DNA binding properties of chelate ring-opening platinum complexes

• Authors: HABTEMARIAM Abraha; NEPLECHOVÁ Kamila; BRABEC Viktor; MARGIOTTA Nicola; SADLER Peter J.
• Year of publication: 1997
• Type: Article in Periodical
• Magazine / Source: Journal of Inorganic Biochemistry
• MU Faculty or unit: Faculty of Science
• Citation: HABTEMARIAM, Abraha, Kamila NEPLECHOVÁ, Viktor BRABEC, Nicola MARGIOTTA and Peter J. SADLER. Unusual DNA binding properties of chelate ring-opening platinum complexes. Journal of Inorganic Biochemistry. Lausanne: Elsevier, 1997, vol. 1997, No 67, p. 161. ISSN 0162-0134.
• web: http://www.sciencedirect.com/science?_ob=MImg&_imagekey=B6TGG-3WCS9CM-4H-1&_cdi=5254&_orig=browse&_coverDate=07%2F09%2F1997&_sk=999329998&view=c&wchp=dGLbVlb-lSzBA&_acct=C000052629&_version=1&_userid=1409883&md5=b6d7f33151d992c1d85a8d8e76925e81&ie=f.pdf
• Field: Biophysics
• Keywords: chelate; platinum complexes; DNA binding
• Description: Bis(aminophosphine) platinum complexes were studied from the point of view of their DNA binding. They were found to show a different binding manner from that of cisplatin.

Related projects

• Structure and Bonding in the Compounds of Nitrogen,Phosphorus,Sulfur and Selenium and in the Complexes of Fe,Co,and Ni with N,P,S-Ligands