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Publication details
Effect of mirtazapine and paroxetine on residual symptoms of depressive disorders and their effect on P450 CYP 2D6 activity
Authors | |
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Year of publication | 2001 |
Type | Article in Periodical |
Magazine / Source | Homeostasis |
MU Faculty or unit | |
Citation | |
Field | Psychiatry, sexuology |
Keywords | depressive disorder-residual symptoms-CYP 2D6-poor metaboliser-extensive metaboliser |
Description | The issues related to preventing a relapse of depressive disorder are high on the list of priorities of psychiatry.The achievement of only a partial remission is a predictor of a higher incidence of relapses.30 patients displaying residual symptoms of depressive disorder were treated with paroxetine or mirtazapine in the conditions of a double-blind study involving monitoring CYP 2D6 activity.Both mirtazapine and paroxetine had a positive effect on residual symptoms of depressive disorder. |
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