Publication details

Využití in situ technik v analýze telomer nádorových buněk

Title in English Aplication in situ techniques in analysis of telomeres of tumor cells
Authors

SKLENIČKOVÁ Marie DVOŘÁČKOVÁ Martina FAJKUS Jiří

Year of publication 2003
Type Article in Proceedings
Conference Analytická cytometrie II
MU Faculty or unit

Faculty of Science

Citation
Field Genetics and molecular biology
Keywords telomeres; FISH; fiber-FISH; PRINS
Description For indefinite cellular proliferation of germline and tumour cells is essential stable telomere maintenance.In most cases, telomere synthesis is performed by telomerase, that results in stabilisation of telomeres.Analysis of telomeres by in situ techniques enables to distinguish between these two mechanisms and analyzes individual telomeres of appropriate cells.
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