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Publication details
Vliv předozáření na některé biochemické parametry maligních nádorů mléčné žlázy: receptory steroidních hormonů
Title in English | Influence of pre-irradiation on some biochemical parameters of breast malignant tumors: steroid hormone receptors |
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Authors | |
Year of publication | 2001 |
Type | Article in Periodical |
Magazine / Source | Klinická onkologie |
MU Faculty or unit | |
Citation | |
Field | Oncology and hematology |
Keywords | breast cancer; estrogen-receptor; progesterone-receptor; radiotherapy; cancer cell; ionizing radiation |
Description | Our results confirm the differences in the expression of steroid hormones in malignant breast tumours with and without pre-irradiation. The results seem to support the assumption that preoperative irradiation of breast tumours may impair the function of estrogen a progesterone signalling pathways in the tumour tissue. The authors believe that a thorough understanding of the consequences irradiation may produce in both healthy and oncologically affected tissue of the mammary gland remains a clinically topical issue even today. |
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