Publication details

Mikrotubulární struktura buněk po účinku Vinca alkaloidů a ultrazvuku

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Title in English Microtubular structure of cells after action of Vinca alcaloides and ultrasound
Authors

BEČVÁŘOVÁ Pavlína ŠKORPÍKOVÁ Jiřina JANISCH Roman ŠTARHA Pavel

Year of publication 2003
Type Article in Proceedings
Conference Sborník abstrakt XXVI.Dnů Lékařské biofyziky
MU Faculty or unit

Faculty of Medicine

Citation
Field Biophysics
Keywords Cytoskeleton; ultrasound; Vinca alcaloides; vinblastin; vincristin
Description Changes of cytoskeletal structures in HeLa cells were observed in presence of various concentrations of vincristin and vinblastin after incubation in duration of 2 - 60 min. There was also followed the action of 1 MHz continuous wave ultrasound. Depolymerization changes of microtubular network have been observed as well as increased occurence of tubuline aggregates.
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