Publication details
Main flavonoids in the root of Scutellaria baicalensis cultivated in Europe and comparison their antiradical properties.
| Authors | |
|---|---|
| Year of publication | 2003 |
| Type | Article in Periodical |
| Magazine / Source | Phytotherapy Research |
| MU Faculty or unit | |
| Citation | |
| Field | Biochemistry |
| Keywords | Scutellaria; flavonoids; baicalin; baicalein; wogonin glucuronide |
| Description | The content of main flavonoids in the root of Scutellaria baicalensis cultivated in Central Europe was evaluated by using new simple RP-HPLC method. The main components of the roots were baicalin-BG (8,12% of dry root mass) and wogonin glucuronide-WG (2,52 %). Five main flavonoids were evaluated for their scavenging ability with DPPH radical and due to limited solubility only two flavonoids were investigated for their ability to scavenge hydroxyl radical by the method aromatic hydroxylation. The total extract was also tested in both the experimental arrangements. In experiments with DPPH only BG and baicalein displayed significant scavenging effect, while the production of OH radical was considerable decreased in the presence of BG and WG. After comparison with results obtained for total extract, it was concluded, that scavenging activity of the extract against DPPH is mainly derived from BG. On the other hand, BG, WG and probably other flavonoids participate in scavenging OH radical. |
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