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Testování bradykardického účinku nově syntetizovaných potenciálních ultrakrátkých beta blokátorů na laboratorním potkanovi
| Title in English | Testing the bradycardiac effect of newly synthesized potential ultrashort beta-blockers on the laboratory rat |
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| Authors | |
| Year of publication | 2004 |
| Type | Article in Periodical |
| Magazine / Source | Česká a slovenská farmacie |
| MU Faculty or unit | |
| Citation | |
| Field | Pharmacology and pharmaceutical chemistry |
| Keywords | bradycardiac effect; rat; ultrashort beta blockers |
| Description | We tested changes in heart rate induced by three newly synthesized potential ultrashort beta-blockers in normotensive laboratory Wistar rats. In all three substances tested, a statistically demonstrable short-time bradycardiac effect was observed. In all three substances tested, marked changes in the ECG record were observed immediately after administration. |