Publication details

Testování bradykardického účinku nově syntetizovaných potenciálních ultrakrátkých beta blokátorů na laboratorním potkanovi

Title in English Testing the bradycardiac effect of newly synthesized potential ultrashort beta-blockers on the laboratory rat
Authors

BARTOŠOVÁ L. FRYDRYCH Marek MOKRÝ P. BRUNCLÍK V. BÉBAROVÁ Markéta

Year of publication 2004
Type Article in Periodical
Magazine / Source Česká a slovenská farmacie
MU Faculty or unit

Faculty of Medicine

Citation
Field Pharmacology and pharmaceutical chemistry
Keywords bradycardiac effect; rat; ultrashort beta blockers
Description We tested changes in heart rate induced by three newly synthesized potential ultrashort beta-blockers in normotensive laboratory Wistar rats. In all three substances tested, a statistically demonstrable short-time bradycardiac effect was observed. In all three substances tested, marked changes in the ECG record were observed immediately after administration.

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