Publication details

Genome differences and detection of pathogenic Treponema pallidum subspecies

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Authors

MATĚJKOVÁ Petra ŠMAJS David NORRIS S.J. WEINSTOCK G.M.

Year of publication 2004
Type Article in Periodical
Magazine / Source Clin. Microbiol. Infec.
MU Faculty or unit

Faculty of Medicine

Citation
Field Genetics and molecular biology
Keywords comparative genomics; Treponema pallidum
Description No extensive differences in genome structure between pallidum and pertenue subspecies including deletions and multiplications of genes using DNA microarray technology have been found. Sequencing showed no deletions and insertions of nucleotides (no ORF shifts). One can predict, that pallidum and pertenue genomes differ in one nucleotide per every 1640 bps (altogether in 700 nts).
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