Publication details
Prolaction levels in risperidone treatment of first - episode schizophrenia
| Authors | |
|---|---|
| Year of publication | 2004 |
| Type | Article in Periodical |
| Magazine / Source | International Journal of Psychiatry in Clinical Practice |
| MU Faculty or unit | |
| Citation | |
| Field | Psychiatry, sexuology |
| Keywords | first-episode schizophrenia; risperidone; treatment response; prolactin; correlation |
| Description | Risperidone in an average dose lower than 4 mg significantly improved both positive and negative symptoms. Co-operating responders undergoing maintanance therapy showed a mild trend towards further long-term improvement. At the end of acute treatment the average elevation of PRL levels almost doubled the baseline value. There was a trend among responders to return to their initial values during long-term therapy. Three-quarters of the subject had hyperprolactinaemia at the end of acute treatment(44 days),and after 1 year about one-quarter had hyperprolactinaemia. No significant correlation between PRL change and PANSS score change was found. |
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