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Publication details
A Method for Detecting Breakpoints in Array CGH data
Authors | |
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Year of publication | 2005 |
Type | Article in Proceedings |
Conference | EnviroInfo Brno 2005. Networking Environmental Information. Part 2. Proceedings of the 19th International Conference Informatics for Environmental Protection. |
MU Faculty or unit | |
Citation | |
Field | Applied statistics, operation research |
Keywords | array CGH; breakpoint detection; analysis; microarray |
Description | In present, microarray CGH experiments became a powerful technique for analysing changes in DNA, by comparing control DNA and DNA of interest. This is widely used for example in genome cancer or species distin-guishing studies. The method produce huge amount of data and special statistic techniques for detecting copy number changes regions are necessary. We propose a new method for detecting breakpoints in DNA. The performance of the method is demonstrated using publicly available data set. |
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