Publication details

Does repeated treatment with MDMA sensitize to its effects on agonistic behaviour in mice?

Authors

ŠLAIS Karel LANDA Leoš ŠULCOVÁ Alexandra

Year of publication 2005
Type Article in Periodical
Magazine / Source European Neuropsychopharmacology
MU Faculty or unit

Faculty of Medicine

Citation
Field Pharmacology and pharmaceutical chemistry
Keywords behavioural sensitization; MDMA; agonistic behaviour; mice
Description In aggressive mice in both groups, vehicle and MDMA pre-treated animals, the drug caused highly significant inhibition of all aggressive activities with the significant increase of defensive-escape behaviour and ambivalent of walking. However, there were no significant differences between group sensitized with vehicle and the other one sensitized with MDMA.
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