Komparativní genomika Treponema pallidum technikou genomové hybridizace na oligonukleotidovém čipu.

• Title in English: Comparative genomics of T. pallidum strains Nichols and SS14 on the oligonucleotide array
• Authors: MATĚJKOVÁ Petra; ŠMAJS David
• Year of publication: 2005
• Type: Conference abstract
• MU Faculty or unit: Faculty of Medicine
• Description: The genome of Treponema pallidum ssp. pallidum strain SS14, the causative agent of syphilis, was sequenced using oligonucleotide arrays. The sequences of more than 49 kb of the SS14 genome were verified by capillary sequencing approach. When compared to T. pallidum ssp. pallidum strain Nichols, the genome of SS14 contained 329 single nucleotide changes (219 transitions and 104 transversions), 7 deletions and 4 insertions.

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