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Poškození fertility a možnosti její ochrany u pacientů podstupujících systémovou léčbu chemoterapií pro Hodgkinův lymfom, literární přehled a vlastní zkušenosti
Title in English | Damage to fertility in patients undergoing system chemotherapy for Hodgkins lymphoma and the options of protecting it in patients of fertile age |
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Authors | |
Year of publication | 2005 |
Type | Article in Periodical |
Magazine / Source | Transfúze a hematologie dnes |
MU Faculty or unit | |
Citation | |
Field | Oncology and hematology |
Keywords | Hodgkins lymphoma; gonadotoxicity; premature ovarian failure; gonadoliberine analoques; sperm cryopreservation; assisted reproduction |
Description | The development of delayed consequences of the antitumour therapy poses an important problem in the treatment of patients with Hodgkins lymphoma. In women, premature ovarian failure develops, causing clinical symptoms due to the lack of estrogens, and resulting in subsequent sterility. In men, serious impairments of sterility are described as early as at the time of diagnosis. |