Publication details

Poškození fertility a možnosti její ochrany u pacientů podstupujících systémovou léčbu chemoterapií pro Hodgkinův lymfom, literární přehled a vlastní zkušenosti

Title in English Damage to fertility in patients undergoing system chemotherapy for Hodgkins lymphoma and the options of protecting it in patients of fertile age
Authors

ŠMARDOVÁ Lenka HUSER Martin KRÁL Zdeněk CRHA Igor VÁŠOVÁ Ingrid WAGNEROVÁ Barbora MAYER Jiří VORLÍČEK Jiří

Year of publication 2005
Type Article in Periodical
Magazine / Source Transfúze a hematologie dnes
MU Faculty or unit

Faculty of Medicine

Citation
Field Oncology and hematology
Keywords Hodgkins lymphoma; gonadotoxicity; premature ovarian failure; gonadoliberine analoques; sperm cryopreservation; assisted reproduction
Description The development of delayed consequences of the antitumour therapy poses an important problem in the treatment of patients with Hodgkins lymphoma. In women, premature ovarian failure develops, causing clinical symptoms due to the lack of estrogens, and resulting in subsequent sterility. In men, serious impairments of sterility are described as early as at the time of diagnosis.

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