Publication details
Analysis of the inducible nitric oxide synthase gene polymorphisms in Czech patients with atopic diseases
| Authors | |
|---|---|
| Year of publication | 2006 |
| Type | Article in Periodical |
| Magazine / Source | Clin Exp Allergy |
| MU Faculty or unit | |
| Citation | |
| Field | Epidemiology, infectious diseases and clinical immunology |
| Keywords | polymorphisms; asthma; atopic diseases; gene; iNOS |
| Description | Nitric oxide (NO) is an important mediator of physiologic processes in the airways; it plays a significant role in the regulation of the Th1/Th2 balance and contributes to the development of atopic diseases. In this stude we analyzed several polymorphisms mainly in the promoter region of the inducible nitric oxide synthase (NOS2, iNOS) gene and investigated their associations with asthma and/or atopic phenotypes. |
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