Dexamethasone suppression test in first-episode schizophrenia

• Authors: ČEŠKOVÁ Eva; KAŠPÁREK Tomáš; ŽOURKOVÁ Alexandra; PŘIKRYL Radovan
• Year of publication: 2006
• Type: Article in Periodical
• Magazine / Source: Neuroendocrinology Letters
• MU Faculty or unit: Faculty of Medicine
• Field: Psychiatry, sexuology
• Keywords: dexamethasone supression test (DST); cortisolemia; first-episode schizophrenia; hypothalamic-pituitary-adrenal (HPA) axis
• Description: Rates of DST nonsuppression in schizophrenia including first-episode schizophrenia are influenced by the stage of illness and medication status. The impairment of feedback regulation of cortisol secretion may be related to different biopathogenetic mechanisms depending on the phase of the illness.

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