Publication details

The influence of paclitaxel on the kidney ultrastructure in magnesium supplemented rats

Authors

SEDLÁČKOVÁ Miroslava WILHELM Zdeněk DRÁBOVÁ Klára DVOŘÁKOVÁ Iva KLEINOVÁ Jana

Year of publication 2006
Type Article in Proceedings
Conference Morphology 2006
MU Faculty or unit

Faculty of Medicine

Citation
Keywords rat kidney; paclitaxel; nephrotoxicity; electron microscopy; magnesium supplementation
Description Alteration of renal parenchyma after paclitaxel administration has been decribed on electron microscopic level. The study of nephron morphology revealed the influence of this drug to impairment of proximal tubule especially. The effect of magnesium supplementation was indistinct.

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