Cytotoxicity and Aryl Hydrocarbon Receptor-Mediated Activity of N-heterocyclic Polycyclic Aromatic Hydrocarbons - Structure-Activity Relationships.

• Authors: SOVADINOVÁ Iva; BLÁHA Luděk; JANOŠEK Jaroslav; HILSCHEROVÁ Klára; GIESY J.; JONES P.D.; HOLOUBEK Ivan
• Year of publication: 2006
• Type: Article in Periodical
• Magazine / Source: Environmental Toxicology and Chemistry
• MU Faculty or unit: Faculty of Science
• Citation: SOVADINOVÁ, Iva, Luděk BLÁHA, Jaroslav JANOŠEK, Klára HILSCHEROVÁ, J. GIESY, P.D. JONES and Ivan HOLOUBEK. Cytotoxicity and Aryl Hydrocarbon Receptor-Mediated Activity of N-heterocyclic Polycyclic Aromatic Hydrocarbons - Structure-Activity Relationships. Environmental Toxicology and Chemistry. Pensacola, FL, USA: SETAC, 2006, vol. 25, No 1, p. 1291-1297. ISSN 0730-7268.
• Field: Environment influence on health
• Keywords: Cytotoxicity;Aromatic Hydrocarbons
• Description: This study presents results of cytotoxicity and Aryl Hydrocarbon Receptor-Mediated Activity of N-heterocyclic Polycyclic Aromatic Hydrocarbons along with their parental compounds determined in a model in vitro system. Structure-Activity Relationship was performed to determine the structural features of the compounds related to the observed effects.

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