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Publication details
Voltage homogenity over the membrane of cardiac cell with a transverse-axial tubular system
Authors | |
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Year of publication | 2006 |
Type | Article in Proceedings |
Conference | Analysis of Biomedical Signals and Images |
MU Faculty or unit | |
Citation | |
Field | Biophysics |
Keywords | cardiac myocytes; voltage homogenity; mathematical model |
Description | The surface membrane of cardiac ventricular myocytes has a complex system of invaginations known as the transverse-axial tubular system (TATS). In order to evaluate the functional importance of the TATS, one question to address is whether the surface and tubular transmembrane voltages differ at rest and during activity. We present here the theoretical background of the passive electrical properties of the interconnected ensemble formed with the surface membrane and the TATS membrane, the latter being simplified to a single compartment. We compare its behaviour with that of our model of ventricular cardiac myocyte with TATS. We conclude that both membrane compartments behave as a homogeneous electrical whole. |
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