Markers of extracellular matrix remodeling, oxidative stress and inflammation in patients with acute myocardial infarction

• Authors: TOMANDL Josef; PAŘENICA Jiří; KALA Petr; POLOCZEK Martin; TOMAN Ondřej; TÁBORSKÁ Eva; ŠPINAR Jindřich; ELBL Lubomír
• Year of publication: 2007
• Type: Article in Periodical
• Magazine / Source: Clinical Chemistry and Laboratory Medicine
• MU Faculty or unit: Faculty of Medicine
• Field: Biochemistry
• Keywords: acute myocardial infarction; ECM; inflammation; oxidative stress
• Description: Recent data suggest that inflammation, oxidative stress and remodeling of extracellular matrix may be associated with the development of heart failure. We assessed the association between circulating levels of soluble intercellular adhesion molecule-1 (sICAM-1), tumor necrosis factor alpha, malondialdehyde (MDA), metalloproteinase-2 and 9 (MMP) and their tissue inhibitor (TIMP-1) in patients with acute myocardial infarction.

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