Repeated administration of methamphetamine downregulates cannabinoid CB1 receptors in VTA of the rat brain.

• Authors: ŠULCOVÁ Alexandra
• Year of publication: 2007
• Type: Article in Proceedings
• Conference: NIDA INternational Forum, 2007, Abstract Book
• MU Faculty or unit: Faculty of Medicine
• Field: Pharmacology and pharmaceutical chemistry
• Keywords: repeated methamphetamine; CB1 receptor downregulation; VTA; rats
• Description: On comparison to the control animals the significantly decreased density of cannabinoid CB1 receptors on neuronal membranes of the VTA was found in methamphetamine treated rats.

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