Publication details
Increased activity of superoxid dismutase in advanced stages of head and neck squamous cell carcinoma with locoregional metastases
| Authors | |
|---|---|
| Year of publication | 2007 |
| Type | Article in Periodical |
| Magazine / Source | Neoplasma |
| MU Faculty or unit | |
| Citation | |
| Field | ORL, ophthalmology, stomatology |
| Keywords | antioxidative enzymes; head and neck cancer; metastasis; oxidative stress; polymorphism; syuperoxide dismutase |
| Description | Our results suggest that increased p-SOD at the time of the initial treatment for HNSCC is connected with a greater extent and nodal metastatic spread of the initial disease and an earlier disease relapse. Progression of diseases might be further modified by the presence of Ala/Ala genotype of the SOD2. Activity of p-SOD could thus offer diagnostic as well as prognostic value. |
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