Acute and repeated exposure to methamphetamine changes expression of CB1 receptor in mesencephalon of the mouse brain

• Authors: LANDA Leoš; JURAJDA Michal
• Year of publication: 2007
• Type: Article in Periodical
• Magazine / Source: European Neuropsychopharmacology
• MU Faculty or unit: Faculty of Medicine
• Field: Pharmacology and pharmaceutical chemistry
• Keywords: PCR; behavioural sensitization; methamphetamine; cannabinoids; CB1 receptor; mesencephalon
• Description: Real-time PCR results showed increased CB1 mRNA expression after both methamphetamine and methanandamide first doses followed by decrease in CB1 mRNA expression observed after the challenge dose of methamphetamine, i.e. in sensitized animals.

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