Publication details
Paramagnetic beads coupled with electrochemical detection as a tool to investigate transcriptome
| Authors | |
|---|---|
| Year of publication | 2007 |
| Type | Article in Proceedings |
| Conference | 35th Meeting of the International Society for Oncodevelopmental Biology and Medicine, ISOBM 2007 |
| MU Faculty or unit | |
| Citation | |
| Field | Biochemistry |
| Keywords | Paramagnetic beads; mRNA; electrochemical detection |
| Description | Paramagnetic beads are mono-dispersive, polymerous particles which have stable and defined surface enabling adsorption and/or linking of different bio-reactive molecules. In addition it is known that each mRNA molecule contains sequence of twenty five adenines. This feature can be used for binding of mRNA on the surface of the beads coated by thymine chains. The present work reports on suggesting and optimizing of mRNA separation and detection from biological material via paramagnetic beads coupled with electrochemical detection. |