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Anxiolytické/antidepresivní účinky kanabinoidu kanabidiolu a kanabinoidního antagonisty rimonabantu ve 2 zvířecích modelech
Title in English | Anxiolytic/antidepressant-like effects of cannabidiol and rimonabant in two animal models |
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Authors | |
Year of publication | 2008 |
Type | Article in Periodical |
Magazine / Source | Psychiatrie, časopis pro moderní psychiatrii |
MU Faculty or unit | |
Citation | |
Field | Pharmacology and pharmaceutical chemistry |
Keywords | cannabinoid; olfactory bulbectomy; social defeat; mice |
Description | Behavioural and immune effects of cannabidiol and rimonabant were studied in the model of bilateral olfactory bulbectomy in rodents and the behavioural effects of both drugs were studied in the social defeat mice mode. These results were compared with data obtained with clinically effective antidepressants and axiolytics. |
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