Publication details

Dendritic cell counts and their subsets during treatment of multiple myeloma

Authors

KOVÁŘOVÁ Lucie BÜCHLER Tomáš POUR Luděk ZAHRADOVÁ Lenka OČADLÍKOVÁ Darina SVOBODNÍK Adam PENKA Miroslav VORLÍČEK Jiří HÁJEK Roman

Year of publication 2007
Type Article in Periodical
Magazine / Source Neoplasma
MU Faculty or unit

Faculty of Medicine

Citation
Web http://www.neoplasma.sk/
Field Oncology and hematology
Keywords dendritic cells; multiple myeloma; flow cytometry
Description Dendritic cells are highly specialised antigen-presenting cells, which can be used for immunotherapy trials. Functionally normal DCs play a critical role in the activation and potentiation of tumour antigen-specific responses, but in some cases they can be defective. The aim of study were analysis of phenotype, finding of differences and/or functional defects in DCs generated from multiple myeloma and monoclonal gammopathy of unknown significance subjects when compared with healthy volunteers under serum-free and/or autologous conditions.

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