Publication details

Dopaminergní mechanismy u deprese a v působení antidepresiv

Title in English Dopaminergic mechanisms in depression and antidepressant drug effects
Authors

ŠULCOVÁ Alexandra

Year of publication 2008
Type Article in Periodical
Magazine / Source česká a slovenská psychiatrie
MU Faculty or unit

Faculty of Medicine

Citation
Field Pharmacology and pharmaceutical chemistry
Keywords neurotransmitter dopamine - depression - mechanisms of antidepressants
Description Both experimental and clinical studies are continuously bringing data suggesting a decreased activity of not only serotonergic and adrenergic but also of dopaminergic brain functioning. This corresponds well with successful therapy of depression with drugs acting either as agonists at postsynaptic dopamine receptors or inhibitors of dopamine reuptake.
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