Publication details

Možnosti aplikace testování aktivity CYP2D6: přehled dosavadních výsledků více než desetileté spolupráce genetiky, farmakologie a psychiatrei

Title in English The CYP2D6 activity testing: results of more than 10 years lasting cooperation of genetics, pharmacology and psychiatry
Authors

ŽOURKOVÁ Alexandra MCCASKEY HADAŠOVÁ Eva FLODROVÁ Eva JUŘICA Jan KAŠPÁREK Tomáš ZAHRADNÍKOVÁ Lucia

Year of publication 2008
Type Article in Periodical
Magazine / Source Psychiatrie, časopis pro moderní psychiatrii
MU Faculty or unit

Faculty of Medicine

Citation
Field Genetics and molecular biology
Keywords personalized medicine; pharmacogenetics; genetic polymorphism; phenotype; genotype; CYP2D6
Description The paper summarizes results of studies of clinical correlates of the CYP2D6 dynamics during the treatment of depressive disorder with paroxetine and points out diffrent clinical outcomes according to gener of patients. Indications for assessmnet of the CYP2D6 are further discussed.
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