Publication details

Genotypová charakterizace kmenů <I>Staphylococcus aureus</I> produkujících exfoliativní toxin A

Title in English Genotype analysis of <I>eta</I>-positive <I>Staphylococcus aureus</I> strains
Authors

HOLOCHOVÁ Pavla RŮŽIČKOVÁ Vladislava PANTŮČEK Roman PETRÁŠ Petr DOŠKAŘ Jiří

Year of publication 2008
Type Article in Proceedings
Conference XVII. konference mladých mikrobiologů Tomáškovy dny 2008
MU Faculty or unit

Faculty of Science

Citation
Web http://tomdny.fnusa.cz/
Field Genetics and molecular biology
Keywords Staphylococcus aureus; bacteriophage; exfoliaive toxins; lysogeny
Description The exfoliative toxin A (ETA) is coded by the eta gene of some S. aureus prophage. The eta-positive S. aureus strains cause the serious disease named staphylococcal skin scald syndrome. ETA-negative strain SAU1039 was lysogenized by eta-phages and was converted into a producer of ETA. Our results indicate that ETA-converting B phages that morphologically resemble the phages of the family Siphoviridae seem to be the major mediators of the eta gene horizontal transfer among the S. aureus strains. We presented the comparative analysis and alignments of the set of the eta-positive strains that were isolated in Czech Republic over years 1998-2007.
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