Subepicardial phase-0 block and discontinuous transmural conduction underlie right-precordial ST-segment elevation in Brugada syndrome by a novel C-terminal SCN5A mutation.

• Authors: BÉBAROVÁ Markéta; 0´HARA Tom; GEELEN Jan; JONGBLOED Roselie; TIMMERMANS Carl; ARENS Yvonne; RODRIGUEZ Luz-Maria; RUDY Yoram; VOLDERS Paul
• Year of publication: 2007
• Type: Conference abstract
• MU Faculty or unit: Faculty of Medicine
• Description: Our data may explain ST-segment elevation on the basis of massive transmural voltage gradients during early repolarization. Reentry-based tachycardia could be evoked during conditions that further exaggerate conduction block in this Brugada phenotype.